With all that talk about Safe Mode, let's now find out how it's done. Creation and access of documents with restricted permission are constrained.Recovered documents cannot be automatically accessed.Changes made in AutoCorrect will not be saved. Customizations made in Safe Mode cannot be saved. The Toolbar will not load with its normal mode customizations.Any additional programs and added features will not be loaded.Here are some limitations of using Excel in Safe Mode: Restrictions of using Excel in Safe Mode If Excel is being run in Safe Mode, it comes with the understanding that there are obviously some features that would not be available as opposed to running Excel in normal mode. The Safe Mode chain only stops when all open files are closed, in other words, when the Excel application is closed. This means that any other Excel file opened will also be in Safe Mode after opening one file in Safe Mode. However, once a file is opened in Safe Mode, the Excel application goes into Safe Mode. You won't be stuck with Safe Mode forever after you open a file in Safe Mode, the next time you open it, it will open in normal mode.

Not to be confused with Windows Safe Mode, Office Safe Mode differs as it runs an Office application in Safe Mode instead of the whole system but the concept is the same launching 'safely'. Safe Mode launches Office applications without some startup programs, extensions, and add-ins that may be causing startup problems so the applications can be used 'safely'.

If Excel is crashing every time it is being opened, you have the option to try running it in Safe Mode.

Opening Excel in Safe Mode from the Command Line.

Opening Excel in Safe Mode with a Keyboard Shortcut.

Restrictions of using Excel in Safe Mode.

Open excel in safe mode